Pharmaceuticals |
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| Session 638 - Continuous Processing in the ChEmical and Pharmaceutical Industry | |||
| Continuous processing has long been applied successfully in all the chemical/material processing industries such as chemical, petroleum, food, plastics etc. Pharmaceutical manufacturing has been dominated by batch processing concept, where each unit dosage form is identified by a batch and tracked accordingly. Over the last decade, many successful efforts have been reported within pharmaceutical manufacturing involving continuous processing. While drug substance manufacturing has lead the way in implementing continuous processing, there is considerable effort being carried out in drug product manufacturing as well. This session invites research efforts and success stories implementing continuous processing for API and drug product manufacturing. | |||
| Chair: | Mayur P. Lodaya | ||
| CoChair: | Ecevit Bilgili | ||
| CoSponsor(s): | Particle Production and Characterization |
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| 638a | Aspects of Screw Design for Wet Granulation Extrusion Michael R. Thompson, Junfeng Sun |
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| 638b | Continuous Production of Active Pharmaceutical Ingredients Using Recycle Derek W. Griffin, Duncan A. Mellichamp, Michael F. Doherty |
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| 638c | Development of Continuous Processes for the Production of Pharmaceutical Substances Using Heterogeneous Catalysis Heidrun Gruber-Woelfler, Rafael J. P. Eder, Birgit Wilding, Iris Pflueger, Peter Feenstra, Gerburg Schider, Alexander Muhr, Christoph Kutschera, Johannes G. Khinast |
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| 638d | Processing Pathway to Enhance Nanoparticle Stability Varun Kumar, Robert K. Prud'homme |
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| 638e | Application of Data Reconciliation, Gross Error Detection and Real Time Optimization for Continuous Pharmaceutical Manufacturing Michelle N. Chaffee, Gintaras V. Reklaitis, Venkat Venkatasubramanian |
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| 638f | Analysis of Operating Conditions of a Continuous Powder Mixer Using Pept Patricia M. Portillo, Andy Ingram, Jonathan P.K. Seville, M.G. Ierapetritou, Fernando J. Muzzio |
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