Session 134 - Batch to Continuous Pharmaceutical Processing Challenges


Topical 5: Green Engineering and Sustainability in the Pharmaceutical Industry
Session 134 - Batch to Continuous Pharmaceutical Processing Challenges
For most companies in the pharmaceutical industry, converting a batch API process into continuous process is likely to go beyond being a technical challenge to the development chemists and engineers. Supporting groups in regulatory, EHS and Quality roles will also be impacted. In this session we want to identify and explore the big challenges facing the development of continuous processes and the conversion of batch to continuous processes.
Chair:	Daniel R. Pilipauskas
CoChair:	Fernando J. Muzzio
CoSponsor(s):	Pharmaceuticals
		Introductory Remarks
	134a	Continuous Processing in Pharmaceutical Process Development ChEnchi Wang, Thomas LaPorte
	134b	Development of Continuous Flow Processes for Pharmaceutical Manufacturing Jerry S. Salan
	134c	Assessing the Effectiveness of a Spinning Tube-In-Tube Reactor James Ciszewski, Michael Gonzalez
	134d	Removing Palladium from Reaction Mixtures by Fixed Bed Adsorption Brian G. Lefebvre, Caitlin A. Boyd, Sonia M. Berberena, Laura E. Kuczynski, Pamela L. Kubinski, Megerle L. Scherholz, Dr. Stephanie Farrell, Robert P. Hesketh, Michael J. Girgis
	134e	Separation of Fine ChEmical Species by Means of Continuous Chromatography: The Simulated Moving Bed Technology Pedro Sá Gomes, Michal Zabka, Viviana Silva, Alírio E. Rodrigues
	134f	Possibility of Separating Enantiomeric Compounds Continuously with Supercritical CO2 and Chiral Ionic Liquids Hiroshi Machida, Wataru Endo, Ryosuke Taguchi, Masaru Watanabe, Yoshiyuki Sato, Richard L. Smith
	134g	Effects of Rotation Rate, Mixing Angle, and Cohesion In Two Continuous Powder Mixers – a Statistical Approach Patricia M. Portillo, Aditya U. Vanarase, M.G. Ierapetritou, Fernando J. Muzzio

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