A new filtration system has been developed, which consists of reactive and/or selective functional multilayer ceramic cakes to remove fine dusts and toxic gases from a variety of air pollution sources. This study presents a method to predict the collection efficiency, cake thickness, cake porosity, and pressure drop across filter cakes during the particulate filtration of gases. The model predicts the cake collection efficiency, which was found to be strongly dependent on the ratio of the mean particle size to the mean pore size of the filter medium. The average cake porosity decreases with increasing cake thickness and the pressure drop increases when the mean particle diameter decreases. The cake height, the pressure profile and the local specific filtration resistance of the system are examined by experiment and theory. It was found that there was excellent agreement between the calculated and measured local pressures. It is possible to design a combination of ceramic filter cakes with the so-called a multilayer model.