333f Complex 3D Scaffolds for Cell Culture

Noy Bassik, George Stern, Mustapha Jamal, and David H. Gracias. Department of Chemical and Biomolecular Engineering, Johns Hopkins University, 125 Maryland Hall, 3400 N Charles Street, Baltimore, MD 21218

Tissues often have complex toplogies, but it is still challenging to construct microstructured scaffolds for culturing cells in non-planar 3D geometries. We describe a strategy to self-assemble complex micropatterned structures such as coils, spirals and cylinders. We investigated the use of these substrates as scaffolds for cell culture in 3D.