Topical A: Systems Biology

Session 251 - Synthetic Systems Biology
Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest.
Chair: Christina Smolke
CoChair: Lingchong You
  Computational Design of Orthogonal Ribosomes In Bacterial Hosts
Lon Chubiz, Christopher V. Rao
  Spatiotemporal Modulation of Biodiversity in a Synthetic Predator-Prey Ecosystem
Hao Song, Meagan Gray, Lingchong You
  Multiple Transcription Factor Binding Sites Can Lead to Noise-Induced Bistability In Gene Expression
Tsz-Leung To, Narendra Maheshri
  Forward Engineering of Synthetic Bio-Logical and Gates
Jonathan R. Tomshine, Kavita Iyer, Jennifer A. Maynard, Yiannis N. Kaznessis
  Multiplex Recombineering: Progress toward the Multigenic Insertion of Regulatory Elements and Potential Applications In Metabolic Engineering
Ryan T. Gill, Joseph R. Warner, Lauren B. Andrews
  Engineering Microbial Production of Glucaric Acid
Tae Seok Moon, Sang-Hwal Yoon, Kristala L. Jones Prather
  Secreting Cellulases from Salmonella
Danielle Tullman Ercek, Christopher Voigt

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